Aerosolized Antibiotics: An Interesting Approach on Multidrug-Resistant Organisms

Picture

Not only the detection but also the treatment of airway pathogens has become a major problem in intensive care units. As mentioned by the WHO multi drug-resistant organisms are a problem and will have a great impact on our clinical work in the future. In all the discussions on restricting antibiotic usage and infection control comes this article by Palmer et al. where they look at actually reducing antibiotic resistance by using antibiotics – Inhaled antibiotics. In itself actually a breach of  paradigm.

In a double-blind placebo-controlled study including a rather small group of critically ill intubated patients they found that aerosolised antibiotics successfully eradicated existing multi-drug resistant organisms and therefore reduced the pressure from systemic agents for new resistance.
While this article is not open access, the editorial by M. Bonten is.

Palmer LB et al. Am J of Resp and Crit Care Med, Vol. 189, No. 10 (2014), pp. 1225-1233

MJM Bonten, Editorial, Am J of Resp and Crit Care Med, 2014

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s